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Multistage analysis method for detection of effective herb prescription from clinical data
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《医学前沿(英文)》 2018年 第12卷 第2期 页码 206-217 doi: 10.1007/s11684-017-0525-8
Determining effective traditional Chinese medicine (TCM) treatments for specific disease conditions or particular patient groups is a difficult issue that necessitates investigation because of the complicated personalized manifestations in real-world patients and the individualized combination therapies prescribed in clinical settings. In this study, a multistage analysis method that integrates propensity case matching, complex network analysis, and herb set enrichment analysis was proposed to identify effective herb prescriptions for particular diseases (e.g., insomnia). First, propensity case matching was applied to match clinical cases. Then, core network extraction and herb set enrichment were combined to detect core effective herb prescriptions. Effectiveness-based mutual information was used to detect strong herb–symptom relationships. This method was applied on a TCM clinical data set with 955 patients collected from well-designed observational studies. Results revealed that groups of herb prescriptions with higher effectiveness rates (76.9% vs. 42.8% for matched samples; 94.2% vs. 84.9% for all samples) compared with the original prescriptions were found. Particular patient groups with symptom manifestations were also identified to help investigate the indications of the effective herb prescriptions.
关键词: effective prescription detection herb set enrichment analysis core network extraction insomnia personalized treatment
遥感和精准农业技术在作物病害检测与管理中的应用实例 Review
杨成海
《工程(英文)》 2020年 第6卷 第5期 页码 528-532 doi: 10.1016/j.eng.2019.10.015
长期以来,遥感技术一直被应用于作物病害的检测和地图绘制工作。在作物生长季节获得的机载和卫星图像不仅可以用于某些病害的早期发现和季节内管理,还可用于未来季节中复发性病害的管控。尽管传统的地毯式杀虫剂施用更适于对付能够迅速在田间传播的病害,然而,在作物病害稳定的情况下,精准农业中的变量控制技术(VRT)亦可以有针对性地对受感染地区的作物有效施用杀菌剂。本文简述了已用于作物病害检测和管理的遥感技术和精准农业技术。具体来说,本文详细阐明了利用机载技术、卫星图像和VRT在棉田中检测棉花根腐病(一种破坏性的土壤传播性真菌病)和绘制分布地图的原理,介绍了从图像中提取处方图以施用定点杀菌剂并有效控制作物病害的方法。本文介绍的案例和方法力图为研究人员、推广人员、种植者、作物顾问、农场设备和化学品经销商提供有关遥感检测和有效管理某些作物病害的实用指南。
通用、有效且轻量的PowerShell解混淆和语义敏感的攻击检测方法 Research Articles
熊春霖1,李振源1,陈焰2,朱添田3,王箭1,杨海4,阮伟5
《信息与电子工程前沿(英文)》 2022年 第23卷 第3期 页码 361-381 doi: 10.1631/FITEE.2000436
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《医学前沿(英文)》 2012年 第6卷 第3期 页码 288-295 doi: 10.1007/s11684-012-0208-4
Tramadol is a potent analgesic. However, the analgesia efficacy of tramadol, particularly its minimum effective dose (MED), is not clear. The aim of this study is to find MED of tramadol for postoperative analgesia in infants. The continual reassessment method (CRM) was performed to find MED. Infants undergoing surgeries were included in the 3 phases of this series. In each phase, 24 participants were allocated a different tramadol dose. Pain intensity was measured by face, legs, activity, cry, consolability (FLACC) measurement at 3-hour intervals. Tramadol was considered ineffective if the FLACC score was higher than 4 in 10 at anytime. In phase 1, seven dose levels were used within the range 0.1–0.4 mg?kg-1·h-1. Phase 1 was insufficient to identify the MED, and we increased the dose to 0.4–0.8 mg?kg-1·h-1 in phase 2. Phase 2 was insufficient to identify the MED. In phase 3, local anesthetic wound infiltration was introduced, and the tramadol dose levels tested were the same as in phase 1. The successful analgesia probability of tramadol 0.4 mg?kg-1?h-1 was 82.1% (95% CI, 0.742–0.925) in phase 1. In phase 2, it was 84.7% (95% CI, 0.789–0.991) with the dose 0.8 mg?kg-1?h-1. Phase 1 and phase 2 were insufficient to identify the MED. In phase 3, the successful analgesia probability for dose 0.35 mg?kg-1?h-1was 96.7% (95% CI, 0.853–0.997).We have demonstrated that tramadol provides insufficient analgesia for surgeries considered to cause moderate-to-severe postoperative pain in infants if used as the sole analgesic, and that local anesthetic wound infiltration enhances the efficacy of tramadol.
关键词: tramadol minimum effective dose postoperative analgesia infants continual reassessment method
Developing effective tumor vaccines: basis, challenges and perspectives
XU Qingwen, CHEN Weifeng
《医学前沿(英文)》 2007年 第1卷 第1期 页码 11-19 doi: 10.1007/s11684-007-0003-9
关键词: development conventional identification elucidation Successful immunotherapy
Z-scheme CdS/WO on a carbon cloth enabling effective hydrogen evolution
《能源前沿(英文)》 2021年 第15卷 第3期 页码 678-686 doi: 10.1007/s11708-021-0768-6
关键词: photocatalysis CdS/WO3 carbon cloth Z-scheme hydrogen evolution
Pijush Samui, Jagan J
《结构与土木工程前沿(英文)》 2013年 第7卷 第2期 页码 133-136 doi: 10.1007/s11709-013-0202-1
关键词: unsaturated soil effective stress parameter Gaussian process regression (GPR) artificial neural network (ANN) variance
OPPORTUNITIES AND APPROACHES FOR MANIPULATING SOIL-PLANT MICROBIOMES FOR EFFECTIVE CROP NITROGEN USE
《农业科学与工程前沿(英文)》 2022年 第9卷 第3期 页码 333-343 doi: 10.15302/J-FASE-2022450
● Matching nitrification inhibitors with soil properties and nitrifiers is vital to achieve a higher NUE.
关键词: nitrogen microbiome NUE rhizosphere phyllosphere soil food web
《环境科学与工程前沿(英文)》 2023年 第17卷 第6期 doi: 10.1007/s11783-023-1671-7
● Dolomite-doped biochar/bentonite was synthesized for phosphate removal.
关键词: Biochar-bentonite composite Dolomite doping Phosphate adsorption Polymeric matrix membrane Adsorption-filtration dual functions Low-concentration phosphate
Pedro PONCE, Therese PEFFER, Arturo MOLINA
《能源前沿(英文)》 2019年 第13卷 第3期 页码 522-538 doi: 10.1007/s11708-018-0562-2
关键词: thermostats perceptions beliefs signal detection theory (SDT) fuzzy signal detection theory (FSDT) chi-square (CS) test
Advances in airborne microorganisms detection using biosensors: A critical review
《环境科学与工程前沿(英文)》 2021年 第15卷 第3期 doi: 10.1007/s11783-021-1420-8
Humanity has been facing the threat of a variety of infectious diseases. Airborne microorganisms can cause airborne infectious diseases, which spread rapidly and extensively, causing huge losses to human society on a global scale. In recent years, the detection technology for airborne microorganisms has developed rapidly; it can be roughly divided into biochemical, immune, and molecular technologies.
关键词: Biosensor Airborne microorganisms Microbiological detection technology
Recent advances in SERS detection of perchlorate
Jumin Hao, Xiaoguang Meng
《化学科学与工程前沿(英文)》 2017年 第11卷 第3期 页码 448-464 doi: 10.1007/s11705-017-1611-9
关键词: perchlorate SERS detection substrate modification nanostructure
UV-LED/P25-based photocatalysis for effective degradation of isothiazolone biocide
《环境科学与工程前沿(英文)》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1379-x
• UV-LED with shorter wavelength was beneficial for photocatalytic degradation.
关键词: Degradation Photocatalytic LED CMIT P25
《环境科学与工程前沿(英文)》 2022年 第16卷 第3期 doi: 10.1007/s11783-021-1472-9
• A spectral machine learning approach is proposed for predicting mixed antibiotic.
关键词: Antibiotic contamination Spectral detection Machine learning
《化学科学与工程前沿(英文)》 2023年 第17卷 第10期 页码 1555-1567 doi: 10.1007/s11705-023-2338-4
关键词: adipic acid loose nanofiltration membrane dye/salt selective separation steric hindrance charge effect
标题 作者 时间 类型 操作
Multistage analysis method for detection of effective herb prescription from clinical data
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期刊论文
Estimation of the minimum effective dose of tramadol for postoperative analgesia in infants using the
null
期刊论文
Developing effective tumor vaccines: basis, challenges and perspectives
XU Qingwen, CHEN Weifeng
期刊论文
Determination of effective stress parameter of unsaturated soils: A Gaussian process regression approach
Pijush Samui, Jagan J
期刊论文
OPPORTUNITIES AND APPROACHES FOR MANIPULATING SOIL-PLANT MICROBIOMES FOR EFFECTIVE CROP NITROGEN USE
期刊论文
Facile fabrication of dolomite-doped biochar/bentonite for effective removal of phosphate from complex
期刊论文
Usability perceptions and beliefs about smart thermostats by chi-square test, signal detection theory, and fuzzy detection theory in regions of Mexico
Pedro PONCE, Therese PEFFER, Arturo MOLINA
期刊论文
A fast antibiotic detection method for simplified pretreatment through spectra-based machine learning
期刊论文